In the final round of the Copa Libertadores 2021 Group Stage today, Junior de Barranquilla will have the last opportunity to jump into the top-two of the group against Independiente Santa Fe, who will finish at the bottom of the standings regardless of their result. Here, take a look at the match information, storylines, predictions, odds, and how to watch the game in the US.

El Cardenal head to this duel after an embarrassing defeat at the hands of a covid-hit River Plate, who humiliated Harold Rivera's boys by grabbing the victory despite having defensive midfield Enzo Pérez in goal and no substitutes. Santa Fe have no chances of getting into the next stage but may spoil Junior's round of 16 hopes.

The side from Barranquilla arrives at this stage alive in the fight for a place in the next round after shocking Fluminense at the iconic Estadio Maracana last week. Will Amaranto Perea's team claim the win it needs to advance?

Independiente Santa Fe vs Junior: Match Information

Date: Tuesday, May 25, 2021
Time: 6:15 PM (ET)
Location: Estadio Bellavista, Ambato, Ecuador

Independiente Santa Fe vs Junior: Time by State in the US

ET: 6:15 PM
CT: 5:15 PM
MT: 4:15 PM
PT: 3:15 PM

Independiente Santa Fe vs Junior: Storylines

Independiente Santa Fe will close a disappointing participation in the Copa Libertadores 2021 with no chances of at least fighting for a Sudamericana spot. Harold Rivera's side was shocked by a weakened River Plate last Wednesday and were left with nothing to play for in the upcoming duel, except for trying to ruin their rivals' aspirations in this tournament.

Junior de Barranquilla remain alive in the group thanks to a huge triumph over Fluminense in Brazil against all odds. Los Tiburones might progress to the next round if they beat Santa Fe and Flu don't defeat River.

They've had ups and downs in their continental path so far, but they still have one remaining shot to push for a place in the last 16. Due to the social unrest in Colombia, this game will be played in Ecuador.

Independiente Santa Fe vs Junior: Copa Libertadores 2021 Standings

After Matchday 5, Junior de Barranquilla stand third in Group D with six points, just two less than Fluminense, who are second, and three away from River Plate, currently first. Independiente Santa Fe, meanwhile, are at the bottom with only two points.

How to watch or live stream Independiente Santa Fe vs Junior in the US

The game between Independiente Santa Fe and Junior for Matchday 6 of the Copa Libertadores 2021 Group Stage to be played in Ecuador will be broadcast in the US by Fanatiz.

Independiente Santa Fe vs Junior: Predictions and Odds

Oddsmakers in the US haven't unveiled their odds yet. However, Caliente has placed its bets and sees Junior de Barranquilla as favorites with -167, while Independiente Santa Fe have +425, and a tie would result in a +300 payout.

Independiente Santa Fe +425
Tie +300
Junior -167

* Odds via Caliente.