The CONMEBOL Copa Libertadores continues next week with soccer action from Matchday 4 from Tuesday, May 11 to Thursday, May 13. So far, only Palmeiras, Argentinos Juniors, and Flamengo have qualified for the Round of 16, while the other teams continue to battle for a spot.

In Matchday 4, Brazilain side Santos host Argentine champions Boca Juniors on Tuesday, May 11. The next day, Wednesday, May 12, Ecuadorian side LDU Quito travel to Liniers, Buenos Aires to come against Velez Sarsfield.

This Matchday provides an opportunity for the bettor to play around with parlays, picks in the over/under, or goalscorers. Here are some betting predictions to consider when placing a bet on these Copa Libertadores matchups.

Santos vs Boca Juniors betting picks (Tuesday, May 11)

Agustin Almendra of Boca Juniors (left) and Vinicius Balieiro of Santos (right) fight for the ball. (Getty)

Agustin Almendra of Boca Juniors (left) and Vinicius Balieiro of Santos (right) fight for the ball. (Getty)

Caliente see Boca Juniors as the firm favorites in this match, considering are the better side in head-to-head games, managing three wins so far in five matches. The Argentine club will enter this game after two poor performances, both in the Copa Libertadores and the Copa De La Liga Profesional. They lost to Barcelona SC and Patronato, 1-0 on both occasions. This will be the perfect chance for them to heal, especially knowing that Santos have not managed two successive triumphs in all competitions since March.

As a result, the Blue and Gold are at +125 to win this matchup while the wager on the underdogs, Santos is at +235. At $100, the bettor could earn $235. Betting that the matchup ends in Under 1.5 goals, for example, is paying out +210, if you want to bet on the clash, might be much more interesting than an outright bet.

Velez Sarsfield vs LDU Quito betting picks (Wednesday, May 12)

Lucas Janson of Velez Sarsfield reacts. (Getty)

Lucas Janson of Velez Sarsfield reacts. (Getty)

LDU Quito are +525 underdogs, and while they did win their first Copa Libertadores matchup with Velez Sarsfield, the oddsmakers don't see the Ecuadorian club repeating the same success. Velez Sarsfield are also on a run of three straight victories in all competitions, and Quito have not grabbed a win in their last two matches in all competitions.

Caliente believe that the Fort will get their revenge on Wednesday, as they are at -200, while if the matchup against the direct second-place rivals ends in a draw, it would mean a payout of +320. Taking the current form of both sides into account, betting that the game ends in a 2-0 win for Velez Sarsfield could be a sure bet, at +550, a $100 bet could earn the bettor $550. 

Parlays for these two matchups of Copa Libertadores Matchday 4

A solid parlay bet could be the following: Santos and Boca Juniors to score Under 1.5 goals, and Velez Sarsfield to win 2-0 over LDU Quito. At $100, the bettor could win up to $760.

Want to stay in the know about all Copa Libertadores fixtures and betting options? Don’t miss a single detail on one of the most prestigious soccer leagues in the world and its possible contenders, thanks to our betting articles right here at Bolavip!