Liverpool and Real Madrid clash again today at Anfield one week after the first leg of the UEFA Champions League quarter-finals that took place at the Alfredo Di Stefano stadium, when the hosts claimed the win by 3-1. The Spaniards head to England with advantage, but the Reds have already completed amazing comebacks in this tournament. Here, you'll find everything there is to know about this game, such as information, storylines, predictions, odds, and how to watch it in the US.

Jurgen Klopp's side faces a challenging situation. While their current Premier League campaign is being quite below expectations, the Champions League remains their only trophy at stake this season. Liverpool has to turn around a two-goal deficit, for which they'll need to be at their best and make no mistakes. Can they go out on Wednesday's clash and have another big night to remember?

Los Blancos, however, made a huge step forward in the first meeting. Zinedine Zidane's team overcame the absence of important players and recorded two important wins lately, first over Liverpool, and last weekend against Barcelona in El Clasico. While they are fighting for La Liga trophy, Real Madrid also proved to be a serious contender to lift the Champions League once again.

Liverpool vs Real Madrid: Match Information

Date: Wednesday, April 14, 2021
Time: 3 PM (ET)
Location: Anfield, Liverpool

Liverpool vs Real Madrid: Time by State in the US

ET: 3 PM
CT: 2 PM
MT: 1 PM
PT: 12 PM

Liverpool vs Real Madrid: Storylines

Liverpool have struggled throughout the Premier League 2020/21, but they started to recover in the last rounds. Still, they were left far away from the top spots, fighting only for a UCL berth. The Reds aren't safe at the current Champions League either, as the defeat suffered at Madrid left them on the verge of elimination. There are 90 minutes remaining, though, which seem to be Liverpool's last opportunity to bounce back this season.

On the other hand, Real Madrid head to this match full of confidence, despite they are dealing with the absences of Sergio Ramos - with injury - and Raphael Varane - who tested positive to Covid. The Merengues claimed a significant advantage at home and even defeated archrivals Barcelona to keep on fighting for the domestic trophy. Zidane's squad is only steps away from progressing to the semi-finals, but they have to be careful at Anfield, where the hosts have already recorded unforgettable comebacks, like the highly-remembered one over Barcelona in 2019.

In knockout stages, Real Madrid advanced in 15 of their last 16 series in which they won the first leg by at least two goals. Meanwhile, the Spaniards have beaten the Reds in the last four games in which they faced, including the 2018 Champions League final. 

Liverpool vs Real Madrid: UEFA Champions League 2020/21 Top Scorers

Liverpool: Mohamed Salah (6)
Real Madrid: Karim Benzema (5)

How to watch or live stream Liverpool vs Real Madrid in the US

The game to be played between Liverpool and Real Madrid in the second leg of the UEFA Champions League 2020/21 quarter-finals will be broadcasted in the US by, ZonaFutbol, Paramount+, Univision NOW, Univision, TUDN USA, TUDN Radio, and TUDN App.

Liverpool vs Real Madrid: Predictions and Odds

Oddsmakers have already placed their bets ahead of this game, and they see the hosts as favorites. FanDuel has given odds of -105 to a Liverpool triumph, while a Real Madrid victory would result in a +250 payout, and a tie in +290.

Liverpool -105
Tie +290
Real Madrid +250

* Odds via FanDuel.