There's no doubt that DeAndre Hopkins is one of the best receivers - if not the best - in the NFL right now. That's why it was such a huge surprise to see the Houston Texans trading him to the Arizona Cardinals for David Johnson and a second-round pick.

More than that, Bill O'Brien must be furious after watching Hopkins pull off one of the greatest catches of all time and - barring a miracle - the play of the year, helping the Cardinals pull off an incredible comeback vs. the Buffalo Bills.

Bills and Cardinals went back-and-forth from the very start of the game, trading big plays, turnovers, and a lot of points. In the end, however, it was the home team the one who came on top thanks to a miracle 'Hail Mary' pass from Kyler Murray and Hopkins' insane catch.

Needless to say, that play didn't go unnoticed around the internet, with NFL players, NBA stars, and pretty much every single person tuning in reacting to that great moment. Here, we'll show you the best memes and reactions to it.

Funniest Memes And Reactions From DeAndre Hopkins' Insane Catch

Notably, this was Kyler Murray's 5th game-winning drive in just one season and a half in the NFL. It's pretty clear that he's special and that's why the Cardinals were so aggressive to try and give him an elite receiver like Hopkins.

The Cardinals are proving that they're a huge threat and that they won't go away any time soon. They feature one of the league's most explosive offenses and their young core is only going to get better with the years.

As for Hopkins, there's just no doubt that he's worthy of a huge payday and that decision to trade him will come back to haunt the Texans for many years to come, especially every time they watch this insane catch.