Deion Sanders faced his toughest challenge as head coach of Colorado at Oregon. In one of the most expected matchups in college football, the Ducks got a resounding 42-6 win.

Colorado had been impressive with a 3-0 record after wins over TCU, Nebraska and Colorado State. According to many experts, their projection was to win two or three games overall. That’s why Coach Prime caught the national spotlight.

Colorado were 21-point underdogs on the road and, without Travis Hunter, Deion Sanders and his players had no response against Bo Nix. Now, there’s still a tough road ahead.

What happens after Colorado lost to Oregon?

Colorado lost to Oregon in Week 4 of college football and now the Buffaloes have a 3-1 record before their toughest game of the year against USC and Caleb Williams on September 30.

Of course, the win by the Ducks put them early in the driver’s seat alongside the Trojans to reach the Pac-12 Championship Game. However, there will be a lot of teams in the mix: UCLA, Oregon State, Washington, Washington State and Utah. It’s going to be a tremendous race.

As Oregon beat Colorado by a wide margin, the Buffaloes most certainly will be out of the Top 25 and they will have no margin of error to win the conference and keep the dream alive of getting into the playoffs.

Nevertheless, it’s already been a huge turnaround for the program and a season of six or seven victories will be a tremendous achievement. Though Coach Prime won’t give up, a Pac-12 title seems almost impossible.

What is the remaining schedule for Colorado?

This is the remaining schedule for Deion Sanders and Colorado after the game against Oregon: USC, Arizona State, Stanford, UCLA, Oregon State, Arizona, Washington State and Utah.