Matchday 1 of the 2021-2022 UEFA Champions League will bring us a mouth-watering game between European giants. Inter Milan and Real Madrid face each other for the second year in a row in this stage of the tournament. Here, you will find everything you need to know about this UCL game that will be played today at San Siro, such as the preview, information, storylines, predictions, odds, and how to watch it in the US.

The reigning Serie A champions head into this tournament aiming to bounce back from last year's disappointing result, when they didn't get past the group phase. Inter have made many changes during the summer, such as hiring Simone Inzaghi following Antonio Conte's departure.

Los Blancos also arrive at this Champions League with a relatively different look. Zinedine Zidane left and Carlo Ancelotti returned for a second stint, captain Sergio Ramos joined PSG, but the rest of team remains unchanged.

Inter Milan vs Real Madrid: Match Information

Date: Wednesday, September 15, 2021
Time: 3 PM (ET)
Location: San Siro

Inter Milan vs Real Madrid: Time by State in the US

ET: 3 PM
CT: 2 PM
MT: 1 PM
PT: 12 PM

Inter Milan vs Real Madrid: Storylines and Head-to-Head

Inter Milan and Real Madrid will be in the same group for the second consecutive year. In the 2020-21 UCL the Merengues won both matches but they picked up just one triumph from their last eight visits (D2 L5) to San Siro.

The Nerazzurri, however, have lost four of the last five meetings with Real Madrid (1W). Inter will try to improve their result of the previous campaign when they finished bottom of the group, while Los Blancos will attempt to reach the final after coming up short in semis at Chelsea, who eventually won the title.

These two have a long history of facing each other in the most prestigious tournament in Europe. Things have been quite even between Inter and Real Madrid so far, with five victories apiece and a draw.

How to watch or live stream Inter Milan vs Real Madrid in the US

The game to be played between Inter Milan and Real Madrid in the 2021-2022 UEFA Champions League opening round will be broadcast in the US by Paramount+, TUDN App, Galavision, Univision NOW, and


Inter Milan vs Real Madrid: Predictions and Odds

Bookmakers in the US have revealed their predictions for this game. FanDuel sees Inter Milan as slight favorites with odds of +145, while Real Madrid have +175, and a tie would result in a +250 payout.

Inter Milan +145
Tie +250
Real Madrid +175

* Odds via FanDuel.