NFL

Latest update on Isaac Guerendo’s knee brings positive news for the 49ers ahead of the 2025 NFL season

The San Francisco 49ers can breathe a sigh of relief following the latest update on Isaac Guerendo’s injury status. However, there’s still a long road ahead to determine if his recovery will be complete in time for the upcoming NFL season.

Guerendo during the NFL Combine
Guerendo during the NFL Combine

The San Francisco 49ers lost several players during the 2024 season, significantly impacting their trenches, which were left severely depleted. However, one of the first pieces of good news regarding injuries has emerged: Isaac Guerendo’s knee isn’t as bad as initially feared.

According to information shared by Matt Barrows, Guerendo’s MRI revealed no ACL damage. Unfortunately, he did suffer an MCL sprain and an ankle sprain, which will keep him in rehab for several weeks during the offseason.

Despite being a rookie, Isaac Guerendo made the most of the 2024 NFL season, playing his first games for the 49ers and contributing 420 rushing yards over 16 games, including three starts. His starts were primarily aimed at filling the void left by Christian McCaffrey, who was limited for much of the season.

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Guerendo’s best scoring performance came against the Chicago Bears, where he recorded two touchdowns. However, his most productive week was against the Seahawks, where he totaled 99 yards, including a 76-yard longest run, though he didn’t score any touchdowns in that game.

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A Secure Future with Guerendo

Despite his injury, the 49ers have Guerendo locked in through 2027 on a 4-year contract worth $4.72 million, which could be upgraded in the coming years. Having such a productive running back gives the franchise a solid starting point for the 2025 season in their running back room.

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49ers’ Rushing Game Struggles

Last season, the 49ers struggled with low production in the rushing game. They ranked 12th in total rushing yards with 2,163 and 15th in rushing attempts with 457, trailing teams like the Broncos and Chargers. In total rushing touchdowns, the 49ers scored 17, placing them 12th in the league standings for rushing performance.

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