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What happened to Saquon Barkley? Eagles RB depth chart vs Rams in 2026 NFL Week 4

The Philadelphia Eagles ran into early trouble against the Los Angeles Rams as Saquon Barkley has once again set off injury alarms in the 2026 NFL season.

Saquon Barkley #26 of the Philadelphia Eagles.
© Michael Reaves/Getty ImagesSaquon Barkley #26 of the Philadelphia Eagles.

The Philadelphia Eagles’ first offensive play of Week 4 against the Los Angeles Rams backfired immediately. On a first-and-10 run play, Saquon Barkley ran out of bounds and came back hobbling and grabbing at his hamstring. After a long wait, Eagles fans have learned they won’t see Barkley back on the field against LA.

“Saquon Barkley (hamstring) has been downgraded to out, Eagles say,” as reported by Andrew DiCecco of Inside The Birds. Barkley was initially considered questionable, but his return has now been ruled out in Week 4.

The fact that Barkley appeared to suffer a non-contact injury and was unable to return for the rest of the drive only raises fears for the Eagles, who also missed Barkley for the majority of Week 2. Behind Barkley, Philadelphia’s running back room includes Tank Bigsby and Will Shipley. The Eagles will count on them to lead them to victory against the Rams.

Needless to say, it’s a nightmare start for Philadelphia at home against Los Angeles. Taking on the Rams, the Eagles were already without both DeVonta Smith and Dallas Goedert. If Barkley is ruled out, Jalen Hurts and Nick Sirianni will be in for an even steeper climb.

Another injury for Barkley

The hamstring injury suffered in Week 4 isn’t the first time this season the Eagles have run into trouble with Saquon. Back in Week 2 of the NFL campaign, the star running back suffered an arm stinger that forced him out of the game early on. So far, Barkley hasn’t been able to get off to the start he hoped for in 2026.

Barkley has 34 carries for 174 rushing yards. He has also caught three passes for only six yards. As shocking as it sounds, Barkley has yet to score a touchdown four weeks into the season.

Key takeaways

  • Out in Week 4 after suffering a non-contact hamstring injury on Philadelphia’s first offensive play.
  • Eagles are already playing without receivers DeVonta Smith and Dallas Goedert against Rams.
  • Saquon Barkley has accumulated 34 carries for 174 rushing yards without scoring a touchdown.
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