Copa America 2021 has just begun but it will already bring us a big derby on Matchday 2. Argentina and Uruguay will face off today, June 18, at Estadio Mané Garrincha in Brasilia to conclude the second round in Group A. Both will be seeking their first win in the tournament, and here you will find the confirmed starting lineups for each national team.

La Albiceleste failed to hold onto their lead against Chile and dropped two points at the beginning of their continental journey. Despite they've created many chances, only Lionel Messi's fantastic free-kick got in. Lionel Scaloni's side needs to get back to winning ways, as it has failed to claim the victory in its previous World Cup Qualifying double-fixture as well.

Meanwhile, La Celeste will make their Copa America 2021 debut against another strong contender to the title. Ten years after their last success, Oscar Washington Tabárez will try to guide Uruguay to a new trophy in what will be Luis Suárez's last Copa America.

Argentina's confirmed lineup

After coming up short with Chile, Argentina will try to get the three points against Uruguay (Getty).

After a bitter draw with Chile in the opening round, Argentina need to make some necessary adjustments to start picking up victories. Their dependence on Lionel Messi could be dangerous, as they can't depend only on one player regardless of his impressive talent. The upcoming clash doesn't look any easy at all, though.

Lionel Scaloni will make a few changes with Cristian 'Cuti' Romero replacing Lucas Martínez Quarta at the back, while Marcos Acuña will take Nicolás Tagliafico's place. Moreover, Sergio Aguero was also in consideration, but Lautaro Martínez will keep his spot as striker.

Therefore, this is how Argentina will line up vs. Uruguay: Emiliano Martínez; Nahuel Molina, Cristian Romero, Nicolás Otamendi, Marcos Acuña; Rodrigo De Paul, Guido Rodríguez, Giovani Lo Celso; Lionel Messi, Lautaro Martínez, Nicolás González.

Uruguay's confirmed starting XI

Uruguay want to begin Copa America 2021 strongly (Getty).

La Celeste head to a new Copa America campaign looking to begin their quest to a new title on the right foot. It's been ten years since Oscar Washington Tabárez led them to continental glory, and this will be the last chance to try it again with Luis Suárez on board.

After the goalless draw with Venezuela on Matchday 8 of the World Cup Qualifiers, Edinson Cavani is eligible again and Tabárez will make a few more changes on the lineup. This will be Uruguay's starting eleven vs. Argentina: Fernando Muslera; Giovanni González, José María Giménez, Diego Godín, Matías Viña; Lucas Torreira, Federico Valverde, Rodrigo Bentancur, Nicolás De la Cruz; Luis Suárez, Edinson Cavani.