San Francisco 49ers and Seattle Seahawks meet in Week 4 of the 2021 NFL season. This game will be held at Levi's Stadium on October 3, 2021 at 4:05 PM (ET). The visitors know how to hurt the home team. Here is all the related information about this National Football League game including the preview, storylines, predictions, odds and how to watch in the US.

The home team want to get the third victory of the season at home, they have a positive record with 2-1-0 in third place in the NFC West Division. But last week things did not turn out as they expected, the team lost to the Green Bay Packer by just two points 30-28 at home.

Seattle Seahawks know they hit dangerous ground, the home team recently lost and they are hungry for another win. The Seahawks have a negative record at 1-2-0. The two losses were back-to-back against Titans and Vikings.

San Francisco 49ers vs Seattle Seahawks: Match Information

Date: Sunday, October 3, 2021.
Time: 4:05 PM (ET)
Location: Levi's Stadium, Santa Clara, California.

San Francisco 49ers vs Seattle Seahawks: Times by State in the US

ET: 4:05 PM
CT: 3:05 PM
MT: 2:05 PM
PT: 1:05 PM

San Francisco 49ers vs Seattle Seahawks: Storylines

The San Francisco 49ers were sore after their home loss to the Packers, it was a tough game from the start but losses must be overcome. This will be the second home game of the season before playing on the road again against the Cardinals in Arizona.

The Seahawks lost the past two weeks, a 30-33 home loss and the most recent on the road 17-30. After this game the team returns home to play against the Los Angeles Rams and then on the road against the Steelers.

Russell Wilson is playing well with 63/86 passes completed, 73.3%, 895 yards, 7 touchdowns with no interceptions. But the Seahawks offense is scoring just 25 points per game. The 49ers have the ninth best offensive line in the NFL with an average of 28.7 points per game.

How To Watch Or Stream Live Free San Francisco 49ers vs Seattle Seahawks in the U.S.

The NFL is available on Television, Radio and Live Streaming on the Internet, this Week 4  matchup and other games will be broadcast in the United States by: Fox,, Fox App, NFL Game Pass. Don't forget to download the app to watch the game on your smartphone.

San Francisco 49ers vs Seattle Seahawks: Predictions And Odds

San Francisco 49ers are favorites at home cpm -3 points to cover and -146 moneyline at FanDuel, they need to win this game at home. Seattle Seahawks are underdogs with +3 ATS and +124 moneyline, totals offered at 52 points. The best pick for this NFL game is: Seattle Seahawks +3.

San Francisco 49ers -3 / -146
Totals 52
Seattle Seahawks +3 / +124

* Odds via FanDuel