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Colorado HC Deion Sanders reveals significant personal news ahead of 2025 season

Colorado Buffaloes head coach Deion Sanders broke his silence about a health issue he has been dealing with.

Head coach Deion Sanders of the Colorado Buffaloes speaks with the media during the Big 12 Media Days at The Ford Center at The Star on July 09, 2025 in Frisco, Texas.
© Stacy Revere/Getty ImagesHead coach Deion Sanders of the Colorado Buffaloes speaks with the media during the Big 12 Media Days at The Ford Center at The Star on July 09, 2025 in Frisco, Texas.

Deion Sanders had been noticeably absent from the spotlight following the end of the last NCAAF season, but his focus is now fully set on what’s ahead. The veteran head coach of the Colorado Buffaloes revealed the reasons behind his time away from football activities.

During a press conference, and accompanied by his medical team, Coach Prime revealed that he had been dealing with a bladder tumor which, fortunately for him, was completely removed — allowing him to continue working as normal.

The news was reported by journalist Tom Pelissero, who shared more details about the announcement through his official X (formerly Twitter) account. The update came from one of the most experienced coaches in College Football.

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“At a press conference, Colorado coach Deion Sanders’ doctors announce they removed a bladder tumor and ‘he is cured from the cancer.’ Sanders implores everyone to get checked out and get the right care. “Without wonderful people like this, I wouldn’t be sitting here today.'”

Colorado Buffaloes HC Deion Sanders

Head coach Deion Sanders of the Colorado Buffaloes watches as his team warms-up prior to their spring game at Folsom Field on April 27, 2024 in Boulder, Colorado.

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A new challenge ahead

With the peace of mind that comes from having overcome a difficult personal challenge in the best possible way, Sanders can now refocus on his passion and look ahead to how he’ll approach the upcoming season with the Colorado Buffaloes.

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Perhaps the biggest challenge right now is figuring out how to replace the departures of last season’s top stars, who are now taking their first steps in the NFL.

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Shedeur Sanders, now with the Browns, and Travis Hunter, now a member of the Jaguars, are perhaps the most prominent examples in this regard, given their incredible stats during their time in Boulder. With a crucial period of preparation ahead, Deion Sanders must now figure out how to fill the significant void they’ve left on the team.

If he can pull it off, there’s no doubt his team will once again be a contender for the National Championship Game — something this program has longed for over the years. Coach Prime is determined to work tirelessly to make it happen.

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