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Is Karl-Anthony Towns playing tonight for Knicks vs Cavaliers in 2025-26 NBA season opener?

The New York Knicks open their 2025–26 NBA season against the Cleveland Cavaliers, but Karl-Anthony Towns’ status remains uncertain ahead of tipoff.

Karl-Anthony Towns #32 of the New York Knicks during a game.
© Elsa/Getty ImagesKarl-Anthony Towns #32 of the New York Knicks during a game.

The wait is finally over — a new NBA season has officially begun. The New York Knicks will open their 2025–26 campaign at Madison Square Garden against the Cleveland Cavaliers, but the big question heading into the matchup is whether Karl-Anthony Towns will be available.

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Towns entered the season dealing with a right quad strain, which put his status for the opener in doubt. However, according to NBA insider Shams Charania, Towns will start in tonight’s game against the Cavaliers.

The inclusion of Towns is a major boost for the Knicks, who will be without Mitchell Robinson (left ankle injury management) and Josh Hart (lower back spasms) to start the season.

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Another player whose status remains uncertain for tonight’s matchup is OG Anunoby, who’s listed as probable with a left ankle sprain. If Towns is unable to suit up, the Knicks will face a major void in the paint with both of their primary big men sidelined.

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Cavaliers also dealing with key absences

For the Knicks, there’s some relief knowing they won’t be the only team shorthanded tonight. The Cleveland Cavaliers will also be missing several key players in their season opener.

Karl-Anthony Towns offers unexpected take on his new role with the Knicks under HC Mike Brown

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Head coach Kenny Atkinson confirmed that starting point guard Darius Garland, starting wing Max Strus, and sixth man De’Andre Hunter will all be sidelined due to injury.

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